Examples are meclizine, dimenhydrinate, and diphenhydramine. The mixed antihistamine/anticholinergic drugs are often available OTC, or "over the counter". Reversible overcompensation if administered after compensation has been attained to a Anticholinergics also affect compensation, producing a The action appears to be mainly central, although there are receptors in both the periphery and centrally. Situation or for a serious disease for which safer drugs cannot be used or areĪnticholinergicswhich affect muscarinic receptors, such as scopolamine, Through D (there is positive evidence of human fetal risk, use only in a life-threatening Pregnancy category varies fromĪ (controlled human studies have failed to demonstrate a risk to the fetus) Table 1: Vestibular Suppressants (order of preference)īenzodiazepine drug dependency, long half life.Īnticholinergic, tricyclic antidepressant,ĭoses are all those used routinely for adults, and will generally not beĪppropriate for children. The antihistamines, and the benzodiazepines. Suppressants, which consist of three major drug groups, the anticholinergics, Imbalance or which reduce motion sickness. One generally used to indicate drugs that reduce nystagmus evoked by a vestibular The term "vestibular suppressant" is a vague Vestibular suppressant and antiemetic drugs are the mainstay We also highly recommend the neuropharmacology review article written by Soto et al (2013).Ī discussion of drug treatment should start with a discussion of the neurotransmitters used to signal in the vestibular system. An older version of this article can be found in print: (Yacovino and Hain, 2012). See also: Drug treatment of central vertigo.Īt a continuing medical education level.
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